Post Learning Implementation Plan (PLIP)

Pre-course

• Access to the Educo Training Portal
• Submit your needs analysis and objectives for training by completing a simple online form

Action Plan

• At the end of the training you will create an action plan to help you implement and develop your new skills and knowledge

Reinforcement Session

• Delivered 3 to 4 weeks after the training
• It is a 1 hour virtual session enabling the group to reinforce the key learnings from the training and cover and subsequent questions and challenges

Day 1

Welcome and Introductions

3D Bioprinting Techniques

• Extrusion
• Inkjet
• Light-based (SLA, DLP and Volumetric printing).
• Introduction to the various techniques will cover:
• working principle,
• key differences (resolution, speed and materials),
• advantages and limitations

Extrusion Bioprinting:

• Review of Printers and Case Study
• Focus on extrusion-based bioprinting with case studies (TBC). Details on hydrogels, cells and pipeline

SLA and DLP Printing:

• Printers and Case Study
• Focus on SLA and DLP printing and bioprinting techniques in healthcare. Case studies (TBC). Details on resins and pipelines (w/w-o cells)

Bioprinting for you 1:

• Establishing bioprinting utility in participants’ research environment.
• Discuss participants’ healthcare challenges and establish projects (max 3) where bioprinting could be of interest

Bioprinting for you 2:

• Establishing bioprinting utility in participants’ research environment.
• Outline potential transferable bioprinting setups and pipelines, including selection of the most suitable bioprinter and materials to give the required resolution, speed, size and cell types

Ethical & Sustainability Considerations:

• Challenges and Opportunities
• What are the current and future ethical and legal implications of cell sources in bioprinting (Consent, Ownership, and Regulations)
• Environmental impact and sustainability of sourcing materials employed in bioprinting
• What opportunities are arising

Day 2

Open-Source Toolkits in 3D Printing:

• RepRap, Fullcontrol, and others.
• Introduce open-source toolkits giving examples and building on:
  • RepRap
  • Fullcontrol
  • Fusion 360 or others
  • Others

PRACTICAL – Extrusion Bioprinter “Hackathon” – Part 1:

• Build your own extrusion printer
• Guided hands-on training to assemble your own 3D bio-printer using open-source technologies
• This will give you hands-on experience of the various stages in setting up a 3D bioprinter and doing your first printing

PRACTICAL – Extrusion Bioprinter “Hackathon” – Part 2:

• Design your own parts, slice and print
• Guided hands-on training to print your own part using an open-source extrusion printer
• This will give you hands-on experience of developing a unique part, slice and print, optimise print and troubleshoot

Emerging Trends & Research Directions in Tissue Engineering:

• Key developments in bioprinting and hydrogels
• Research advances and breakthrough in achieving large, rapid and high resolution bioprints
• Developments in 4D bioprinting: dynamic and stimuli responsive structures

Emerging Trends in Industrial Applications:

• Key developments in additive manufacturing and hydrogels
• Bioprinting in Pharmaceutical Companies and Manufacturing Catapults with a focus on wearables, sensors and drug development
• Integration of Bioprinting with AI and Machine Learning

Dr Gowsihan Poologasundarampillai (MEng RSMA PhD DIC) is an Associate Professor in Biomaterials and Biomanufacturing at the University of Birmingham. He has over 20 years of experience on biomaterials and biomanufacturing with over 60 publications and 5 patents. His research group is focused on developing novel hydrogels for application in 3D bioprinting with funding from several UK Research and Innovation councils and industries.

Dr Amirpasha Moetazedian (BMedSc MSc PhD) is an Assistant Professor (lecturer) in Medical Engineering at the University of Hull. He has over 6 years of experience on additive manufacturing of bioresorbable polymers for biomedical applications with over 20 publications. He created the new design approach for extrusion-based additive manufacturing “CONVEX” to enable microscale control of the print path for personalised medical devices. His research group is focused on integrating AI into CONVEX design approach to develop the next generation of smart wearable microfluidic sensors for digital healthcare monitoring.

Dr Sam Moxon (BSc, PhD) is a Senior Research Fellow in Chemical and Biomedical Engineering. He has over a decade of experience in biomaterials and additive manufacturing with a strong track record of publishing pioneering research in the field. In 2017 Sam established a new form of bioprinting that is now widely utilised internationally and his research now focusses on applying additive manufacturing methods to the field of medical research.