Post Learning Implementation Plan (PLIP)

Pre-course

• Access to the Educo Training Portal
• Submit your needs analysis and objectives for training by completing a simple online form

Action Plan

• At the end of the training, you will create an action plan to help you implement and develop your new skills and knowledge

Introductory Module 1

FREE to Attend | Live & Recorded

Sign up

31 October 2025 | 60 mins | 1:00 PM UK

Fundamentals of pharmacokinetics

• Role of PK
• Absorption
• Distribution
• Metabolism
• Excretion
• Disposition

Register For Module 1 | Free

There are limited spaces on module 1. If demand is high you may not be able to attend the live session, however you will be sent the recording. Priority is given to full registrations.

Module 2 & 3

24 November 2025 | 150 mins | 1:00 PM UK

Pharmacokinetic analysis

• First and Zero Order Processes
• Non-compartmental Analysis
• Compartmental Analysis
• Elimination Half-life
• Clearance
• Volume of Distribution
• Case study

Drug-Drug interactions

• Definitions of drug interactions
• Drug metabolism
• Enzyme inhibition and induction
• Reaction phenotyping
• Study design
• Transporter interactions
• Case study

Module 4 & 5

25 November 2025 | 150 mins | 1:00 PM UK

Regulatory guidelines

• PK Results Presentation
• Individual and mean PK Profiles
• Variability in PK
• Crossover Study design
• Statistical Analysis
• Sample Size Calculation
• First In Man Guideline

PK/PD studies

• Single and Multiple Dose PK Studies
• Linear PK
• Absolute and Relative Bioavailability, Bioequivalence
• Food Effect study

Module 5 & 6

26 November 2025 | 150 mins | 1:00 PM UK

PK/PD studies

• Biomarkers
• Direct vs Indirect PK/PD
• Hysteresis

Pharmacokinetics of biologics & population pharmacokinetics

• Definitions of Biological Drugs
• Biological Drugs ADME
• PK of Biological Drugs Guideline
• Fundamental of Population PK
• Role of Population PK
• Application of Population PK

Dr. Stefano Persiani is currently Director of Translational Sciences and Pharmacokinetics at Rottapharm Biotech, Italy. After years working in academia, Dr. Persiani moved to the pharmaceutical industry and CRO sector holding different positions always applying pharmacokinetic approaches in R&D at Farmitalia Carlo Erba, Pharmacia, Upjon, and Zambon Group.

His experience within pharmaceutical companies and CROs includes the assessment of pharmacokinetics, drug metabolism, and drug-drug interactions during drug discovery for lead optimization and in preclinical as well as in clinical pharmacology during drug development. He has experience addressing pharmacokinetic issues for drugs and biologics under development in different therapeutic areas including oncology, respiratory, CNS, anti-infective, cardiovascular, gastrointestinal, and rheumatology. In these therapeutic areas, he applies translational, PK/PD prediction, and modelling strategies for candidate selection and to obtain the proof of concept of efficacy and safety in preclinical models as well as during clinical trials in the target patient populations. Dr. Persiani regularly interacts with regulatory authorities and acts as peer reviewer of scientific articles in the field of pharmacokinetics and clinical pharmacology.